Sentence examples for involve significant changes from inspiring English sources
"It would involve significant changes to how central government operates".
The obtained results indicate that estimation of the position at a sufficient accuracy for most of the location-based services does not have to involve significant changes in the terminals and in the network infrastructure.
This might involve significant changes in the physiology and metabolism of individuals under selection [ 25].
However, the process of early IVD degeneration may also involve significant changes in NP progenitor/stem cells, and these cells may have a significant influence on the biomolecular signaling events within the NP.
As the LTT can account for more than 50% of the total signal change between 8 °C and the fully denatured state (∼70 90 °C), it must least involve significant changes to hydrogen bonding or helical twist if it were not helix unfolding itself.
We conclude from these observations that TGIF induces TGFβ-mediated transcriptional regulation in the epithelial cells of the mouse middle ear at time when the mutant mice develop OM and that this regulation does not involve significant changes in the distribution of the cPML activator protein.
It will engage better with commercial operators, with, for the first time, an expectation that BBC management will actively seek industry reactions to any initiative in an area of particular market sensitivity that is likely to involve significant change.
Marketing innovation is the implementation of a new marketing method involving significant changes in product design or packaging, product placement, product promotion or pricing [17, 18].
"Without question we're in a period of transition that involves significant changes in the way we do business," Wetherell says.
It should also be stressed that the implementation of activation strategies in OECD countries has generally involved significant changes in labour market policy institutions, legislation, and management principles, as well as in the design of specific programmes.
The transformation of Poland's economic system in the 1990s as a result of transition from a centrally planned economy to a market-based system involves significant changes in the regulatory context and in accounting practice and education.
