Sentence examples for involve mutation of from inspiring English sources

Currently, the most commonly used molecular evolution processes involve mutation of a single gene into complex gene repertoires followed by selection from a display library.

The above-mentioned SCA types all involve mutation of UPS component proteins (Table  1).

Future experiments will involve mutation of this amino acid and correlating it with GmRLK18-1 stand/ory and/or function in binding the CLE like peptide motifs found in all plants and their many of their pathogens [ 30].

More than half of all known cancers involve mutations of p53, a tumor suppressor protein present in every cell which regulates the cell cycle and signals for cell death in the event of damage to DNA.

They can involve mutations of BCR pathway components or be triggered by antigens present in the tissue microenvironment [ 6].

The latter observation is consistent with the fact that a large number of AMLs involve mutations of C/EBPα (Preudhomme et al., 2002).

If higher levels of resistance require a cell to devote more resources to detoxifying or eliminating a drug or involve mutations of greater phenotypic effect, we might expect a negative relationship between MIC and fitness.

Hereditary nonpolyposis colon cancer associated cancers arise from MLH1 and MSH2 germline mutations and rarely involve mutations of other genes (Liu et al, 1996; Peltomaki and Vasen, 1997) or MLH1 promoter region methylation (Wheeler et al, 2000; Potocnik et al, 2001; Yamamoto et al, 2002).

Patients affected by cerebral creatine deficiency syndrome-1 (CCDsharehare depletion of brain Cr and the clinical phenotype with patients carrying the other two defects of Cr metabolism which involve mutations of genes encoding the biosynthesizing enzymes AGAT and GAMT (Item et al., 2001; Stockler et al., 1994).

Resistance to oxazolidinones also involves mutation of 23S rRNA, resulting in decreased binding affinity.

The underlying cause of ampullary cancer is complex, involving mutation of oncogenes, silencing of tumor suppressors, alteration of cell adhesion molecules, and activation of tumor-associated macrophages [ 7– 9].