Sentence examples for involve downstream from inspiring English sources
Even though the ligand-binding assay can be performed readily with desirable precision and accuracy, the mechanism of action could involve downstream events post ligand-binding.
These data indicate that vHP-mediated feeding effects involve downstream Ox1R signaling.
The noncanonical signaling pathways involve downstream PI3K/Akt, Ras small GTPases, Wnt/β-catenin, ERK, p38, and JNK.
The molecular signatures of alcohol-induced TLR tolerance and sensitization, respectively, have been well described and involve downstream components of the TLR-induced signaling cascades.
If this reduction is relevant to PAH pathogenesis, the mechanism may involve downstream signaling by BMPR2 that is not along the canonical BMPR2 signaling cascade.
In addition, PIK3CA mutations are a major determinant of resistance to trastuzumab and appear to involve downstream signaling pathways such as PI3K/AKT [33], [35], [35].
Such closely connected local systems are termed biotope systems, the most obvious linkages in this case involving downstream drift of organisms during regular flow stages and especially during intervals of high discharge (floods).
These findings suggest that alternative models for hormonal control of avian clutch size need to be considered, perhaps involving downstream regulation of plasma PRL at the level of the ovary, or other hormones that have not been considered to date.
The resultant signal, termed as dynamic mass distribution (DMR), is an integrated and whole cell response that reflects signaling pathway(s) involved downstream the receptor activation [13] [15].
The present work was designed to elucidate the signalling pathways involved, downstream D2 receptor (D2R) stimulation, in striatal vulnerability to ExpHtt.
The specific pathway involved downstream of this Wnt1/Xfz3 is very likely the canonical Wnt/β-catenin pathway, although this has not been addressed in detail.
