Sentence examples for involve depletion of from inspiring English sources

Given that Hha is toxic (Figure 2) and represses the transcription of argU and proL, we hypothesized that part of the toxicity mechanism may involve depletion of rare codon tRNAs since the diminution of specific rare codon tRNAs by minigenes is toxic with the rare arginine AGG and AGA codons (argU) and the rare isoleucine ATA codon (ileX and ileY) most toxic [41].

The precise mechanism of mTORC1 inhibition by TAIII remains to be determined, but it involves growth factor activated proliferative pathways (Figure 4B) and does not involve depletion of energy stores (ATP levels are not affected in cells treated with TAIII or BN108; data not shown).

Alterations in intracellular calcium balance involve depletion of ER calcium stores and reduced SERCA activity.

The comparative proteomic workflow involved depletion of high abundance proteins, 2D-DIGE analysis and protein identification by LC-MS/MS.

The same lack of reciprocity also argues against a mechanism involving depletion of the Mipp1 substrate IP6 or its alternative substrate 2,3-bisphosphoglycerate (2,3-BPG) [21].

This led to the remarkable and surprising finding that all the treatments tested involving depletion of either cholesterol or sphingolipids –two lipid classes enriched in DRM- result in increased LTB4 and PGE2 synthesis.

Hyperactivation of PARP-1 results in caspase-independent non-necroptotic cell death, which involves depletion of NAD+ and cellular ATP.

Experiments involving depletion of CD8 T cells confirmed their role in cytolytic and non-cytolytic effects on viral clearance.

The progressive degeneration of articular cartilage involves depletion of ACAN and the deregulation of matrix components, such as proteoglycan and collagen [ 2].

To effectively examine the timing at which individual components assemble into the satellite, we started with a highly synchronized mitotic cell population by employing a metaphase arrest/release protocol involving depletion of the anaphase activator Cdc20.

It is a hopeful sign that some rural communities in the West have charted a path to economic health that does not involve the depletion of natural resources.