Sentence examples for involve considerable expense from inspiring English sources
With respect to feasibility, numerous agents would have to be sampled many times in each area assessed, which would involve considerable expense.
Although there is no need to repeat all trials of the reference biopharmaceutical, the need to conduct some biosimilar trials enrolling several hundreds of patients involve considerable expense and time: a US study has estimated that the costs of biosimilar trials would range from US$10 to $40 million.
The accused might appeal to the pope before proceedings began, but this involved considerable expense.
When a crane or dolly was used to shoot the live portion of the scene, the background had to be animated frame-by-frame, involving considerable expense in draftsmanship.
The public health response to this outbreak involved considerable expense.
Domestic heating in winter involves considerable expenses, so the idea of energy conservation and the need to implement reliable and innovative solutions in the field of energy in constructions emerged.
While highly effective, these methods are largely confined to laboratory settings, require trained personnel and can involve considerable time and expense.
"The main deficiency of ATW," explains Philip Connolly, campaigns officer at the Royal National Institute for Blind People, "is employers' ignorance of it - either they have never heard of it or they think it will involve a considerable expense".
First, the construction of GMP-compliant viral vectors requires extensive validation and involves considerable cost in terms of expense, specialized reagents and labor.
