A sequence of specific cellular events involving cell differentiation is required to form a mature TE and the study of this process in planta is difficult because differentiation occurs within complex tissues in the plant body.
The fifth GO module involved regulation of receptor activity (GO 0010469), and the sixth module involved cell differentiation (GO 0030154).
It has been shown that this nuclear receptor is important in several biological pathways involving cell differentiation, insulin sensitivity, atherosclerosis and cancer (Rosen and Spiegelman, 2001).
Since the serpin genes are expressed in callus, which is undifferentiated tissue, the serpins themselves are unlikely to be required only for processes involving cell differentiation.
When phenotypic switching of smooth muscle cells to an osteogenic phenotype is achieved in vitro using a common osteogenic milieu, it involves cell differentiation and expression of alkaline phosphatase to hydrolyze phosphoric acid monoesters into free phosphate ions [ 35].
MiRNAs play essential roles in many normal biological processes involving cell proliferation, differentiation, apoptosis, and stress resistance [ 26, 27].
Among these aberrant miRNAs, the downregulated miR-200b and miR-200c (miR-200b/c) have been reported to involve in cell differentiation and epithelium malignancy in cancer9,22.
It is not presently clear whether the predator-induced morphological changes to tadpole tail morphology involve a cell differentiation process.
At PI, both diets invoked a clear down-regulation of genes involved in cell differentiation and proliferation, some involved in cell to cell communication, cytokines and several PRR.
The signaling cascades involving JNK and p38, activated by extracellular stress signals, are involved in cell differentiation and apoptosis [17], [18].
In particular, this includes determinants of cell fate and transcription factors involved in cell differentiation within specific tissues, as well as signalling pathways involved in general organogenesis.
