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Most denitrification methods therefore involve alteration of physical or chemical conditions through the use of inhibitors (e.g., acetylene) or amendments (e.g., 15N) that produce inaccurate or unrealistic estimates of rates.
Further potential KCR1-induced regulatory mechanisms might involve alteration of HCN trafficking and cell-surface stability.
Not only does the inhibitory mechanism involve alteration of the proliferation of cancer cells, but also induction of apoptosis.
Increasing evidences suggest that the related processes of neoplastic transformation involve alteration of the normal apoptotic pathway [ 8].
Four mutants, T39R (TM1), G46R, D47H, and D47Y (TM1-EC1 junction), involve alteration of surface electrostatic potential and T39R also involves steric clash induction with adjacent subunit; those would probably undergo impaired trafficking.
The most studied plant behaviours involve alteration of aboveground morphology to optimize access to sunlight (Smith 2000; Novoplansky 2009), or of reproductive or defensive traits to deal with environmental heterogeneity (Karban 2008).
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We conclude that the mechanisms of rapamycin resistance in hepatic cells involve alterations of signaling downstream from mTOR and that the mechanisms are highly heterogeneous, thus predicting that maintaining or promoting sensitivity will be highly challenging.
During the symbiotic interaction, both partners undergo significant morphological and physiological modifications which involve alterations of the metabolite profile [ 1– 4].
Evidence from human tumors uncovered multiple mechanisms through which cyclin D1 expression is deregulated, most of which involve alterations of the CCND1 locus itself (Musgrove et al, 2011).
These β-catenin mutations involve alterations of exon 3 of serine/threonine sites that normally are phosphorylated by glycogen synthatase kinese 3 β (GSK-3 β).
These developmental and phenotypic similarities are intriguing and suggest that the causes of positive selection on these genes may involve alterations of common neurogenetic pathways.
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