Sentence examples for involve a direct effect from inspiring English sources
Collectively, these data indicate that the mechanism does not involve a direct effect on the cardiovascular system and is most likely via a hormonal or endogenous mediator system.
It seems conceivable that the role of PGE2 in tumor repopulation after treatment could involve a direct effect on cancer stem cells.
However, we found that CD200R1 expression was also decreased on CD4+ T cells and at least the activity in regulating Tregs appeared to involve a direct effect on T cells.
The mechanism of bacterial cell death may involve a direct effect of the LCBs on the bacteria (Fischer et al, 2012), or possibly up-regulation of porin-like proteins that are responsible for channel formation in the bacterial membrane (LaBauve & Wargo, 2014).
3, 70 The exact mechanism by which SGLT2 inhibition and uric acid reduction are related is unknown, but may involve a direct effect on renal uric acid transport or an indirect effect secondary to corresponding decreases in sodium reabsorption in the proximal tubule.
Because the level of OmpX detected is also increased in TET induced strains (Figure 2), we propose that the regulatory role for this OMP involves a direct effect on porin assembly.
These results also support that the mechanism may involve a direct toxic effect of smoking exposure during pregnancy.
Although the mechanism by which bortezomib induces thrombocytopenia is unknown, murine studies suggest that it does involve a direct cytotoxic effect on megakaryocytes or alteration in thrombopoietin (TPO) levels.
The mode of action of clarithromycin might involve either a direct effect on the test isolate or its intervention on the inflammatory cascade.
The mechanisms underlying the therapeutic benefit of LNA-92a very likely involve a direct pro-regenerative effect on local ECs adjacent to the injury, which secondarily influences leucocyte accumulation and SMC proliferation.
The study did not involve a direct intervention; thus, the behavioural effects of the messages tested cannot be estimated.
