Our strategy is designed to invoke feedback activation of signals within yeast G-protein signaling pathways.
Unlike earlier work, this paper identifies parts of the state space where it is possible to invoke feedback linearization and uses the closed-loop paradigm [8] to accommodate input constraints while utilizing an extremely efficient online receding horizon strategy.
Potential direct binding of klf2, klf4, and lin28b, which mostly encode transcription factors that could invoke feedback loops as has been previously reported, was also examined (Fig. 4).
It must be noted, however, that while the close match between our theory and experiment without invoking any feedback control implies that any feedback control mechanisms operating on endomembrane organelle copy numbers are no more precise than the biogenesis system could achieve without feedback, we do not explicitly rule out the presence of feedback regulation of the organelle copy numbers.
We discuss theoretical models that invoke mechanical feedback loops for growth regulation and experimental studies providing empirical support.
In this case, the extended repetition of the melody may also invoke a feedback loop in which the auditory system operates in an oscillatory mode, reinforcing the rhythmic nature of the passively-attended stimulus [66], [67].
First, budding yeast cells tolerate the maximum level of variability generated by the biogenesis pathways governing Golgi apparatus and vacuole abundance, evidenced by the fact that our model predicted the experimental data with high quantitative accuracy without invoking any feedback control mechanisms to control the number of organelles.
Stimulation of cultured E18 HIP neurons by growth factors invokes a negative feedback mechanism involving the vesicular translocation and activation of TRPC5 channels in the membrane of neuronal growth cones leading to the cessation of growth [10].
The auxiliary output is used for closed-loop control with positive feedback invoking the internal stability condition of negative-imaginary theory.
Astronomers invoke such a "feedback" scenario involving black holes to explain the paradox of why galaxies haven't grown to sizes much bigger than those seen today.
This scenario can occur when plants invoke a positive feedback loop that amplifies ROS to serve as signaling molecules [ 28, 41].
