Exact(1)
The investigators derived iPSC lines from patients with the LRRK2 mutation and healthy individuals without the mutation; they also used genome editing to correct the mutation in the mutant iPSC lines.
Similar(59)
Questionnaires consisted of validated scales and investigator derived questions.
Both single item investigator derived questions and standardized instruments were used.
Based on peer review and professional commitment, an investigator derived questionnaire (see additional file 1: German Federal Police questionnaire on railway suicides) was developed to assess knowledge and experience of German Federal Police officers with railway suicide in a quantified manner.
The questionnaires, which were composed of both standardized scales and investigator derived questions, asked about socio-demographics, lifestyle, heath care utilization, mental health, social support, birth outcomes, postpartum experiences, and breastfeeding, among other variables.
The scepticism of many investigators derives from the notorious instability of RNAs, which are susceptible to artificial degradation during experimental manipulations, resulting in experimental artefacts.
However, EIP investigators have derived great pleasure in training the next generation of public health epidemiologists, and this has yielded dividends for mentees, mentors and public health.
In a study of smelter workers in Tacoma, Washington, investigators empirically derived the following relationship between inhaled and urinary arsenic levels: airborne arsenic in micrograms per cubic meter = 0.0064 (urine arsenic in micrograms per liter)1.924 (Enterline et al. 1987).
There are several reasons for which the concept of MID seems useful and investigators should derive it from patients.
Consistent with this, investigators commonly derive 'normal' cell lines from primary human mammary epithelial cells that, surprisingly, are nearly always ER-negative.
A plot like this provides a visual inspection of the read coverage of RNA-seq samples and can help an investigator derive useful information from suboptimal tissue, while guiding decisions regarding whether a sample should be discarded or not.
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