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Such scenarios are difficult to test experimentally but are currently under investigation using modeling approaches.
The potential of those techniques used in combination was demonstrated with a toy model and the results are encouraging for investigations, using operational models.
Investigations using animal models that simulate clinical epilepsy are imperative.
This indicates the need for further investigations using animal models of TB.
Finally, investigations using monkey models are justified by α-synuclein features unique to the primate brain (e.g. age-related upregulation) that may contribute to pathogenetic processes [20] [22].
Investigations using animal models will be conducted in the future.
Further investigations using fly models could provide insight into the mechanisms involved in hypothermia-associated neuroprotection.
Toxicological investigations using animal models are both expensive and time taking.
Thus, further investigations using other models of divergence with larger DNA data sets are needed to address the detailed demography.
Investigations using glioma models have already provided a wealth of information on the biological mechanisms responsible for glioma cell migration.
Nutritional epidemiology studies have served as a vital signal of associations that sometimes point to the need for additional investigations using animal models and/or human intervention trials.
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