Clearly, functional studies of venoms and translated products of MIL2 and MIL3 alleles and especially their effects on prey as well as investigations of functions of gene products and patterns of variation of other conotoxin loci are needed to illuminate the bases of these selection pressures.
Investigations of functions and connections of the IC suggest that sensory information including gustatory, olfactory, visual, auditory, and tactile inputs converge on IC, and that these multimodal sensory information may be integrated there.
An investigation of function and expression patterns of genes elucidate the regulation mechanism underlying the important developmental processes cell division and kernel filling.
Investigation of function in gar embryos could help resolve these types of questions.
The detailed investigation of function of RNAs derived from telomeres and the epigenetic control of telomeres will foster our understanding of general telomere regulation.
Since a source of expression data in UC is unavailable for some of the genes of interest, it will be important to demonstrate an inverse relationship between hypermethylation and expression of a gene before further investigation of function in UC.
For example, about half of intergenic DE bins overlap ESTs (Table 3), with the majority of them overlapping EST introns (Table 3), suggesting that the labels "intron" or "exon" should not influence an unbiased investigation of function.
Topologies of G-quadruplexes depend on oligonucleotide sequences and on environmental factors, and the diversity of G-quadruplex topologies complicates investigation of functions of these nucleic acid structures.
The blocked design we employed in our previous studies [3], [4] did not allow investigation of function-specific changes in brain activity associated with encoding and response selection.
Therefore, further investigation of functions of epithelial cells in the immune and inflammatory responses can not only aid in understanding the pathophysiological basis of airway diseases, but also help for the future therapeutical invention of these diseases.
