Improved linkages between relevant databases (such as searchable patent and investigational new drug applications with the federal grant database) will assist with attribution of near-term and intermediate outcomes to research funding.
Finally, NPC is a database of approved and investigational drugs for high-throughput screening.
The NCGC-NPC is an established, broad, and open access database of approved and investigational drugs enabling repurposing and chemical genomics [ 20].
At the time of this study, the DrugBank database contained 7000 approved, withdrawn, investigational, and experimental drug compounds for download [47].
Clinical, pathological and investigational data were recorded prospectively on a computer database allowing analysis for prognostic factors.
69 Currently most investigators regard combination therapy as investigational.
The DrugBank database includes chemicals classified under various categories [47]: approved, investigational, illicit, and experimental.
After approval from the Investigational Review Board of the University of Pittsburgh we searched the database of Medical Archival Systems Inc. (Pittsburgh, PA, USA) from 1 January 2001 to 30 June 2002 for all ICU admissions at the University of Pittsburgh Medical Center, Oakland, PA.
Taken together, these data indicate that, as designed, clinical trial databases capture potential drug-related events and complications associated with investigational therapies.
There may be a need to formalize: standards, metadata and investigational design for all contributors to share compatible results: procedures to monitor and control the project; and document and database design to deliver a uniform product.
