Sentence examples for investigating gene expression changes from inspiring English sources
The list of ToxArray™ genes was compiled from our own data, as well as extensive information from published studies investigating gene expression changes, assessed using microarrays or other technologies, following toxicant exposures.
We hypothesized that investigating gene expression changes that are associated with the improvement in the phenotype seen in temsirolimus treated ataxin-3 transgenic mice would allow us to identify gene expression changes that are important in the progression of the disease, since temsirolimus administration reduces the levels of the primary 'toxin', mutant ataxin-3.
Thereafter, transcriptional study including cDNA microarray in combination with suppression subtraction hybridization (SSH) was used to investigate gene expression changes in the mutant, and a total of 267 differentially expressed genes were detected [ 12].
Therefore, a transcriptional study including a cDNA macroarray in combination with suppression subtraction hybridization (SSH) was used to investigate gene expression changes in the MT, and a total of 368 differentially expressed genes were detected [ 22- 25].
To investigate gene expression changes possibly related to the growth rate recovery, quantitative reverse transcriptase PCR and 2DE proteomic studies were performed.
These findings further underline that transcriptomics approaches described represent a useful way to investigate gene expression changes in Hbt. salinarum.
In addition, we also analyzed the testicular transcriptome of VRK1-deficient mice using DNA microarray and quantitative RT-PCR to investigate gene expression changes of specific markers during the first wave of spermatogenesis in postnatal mice.
Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium tuberculosis, a major human pathogen, and its human host cells, macrophages and dendritic cells.
Our current genome-wide study is designed to investigate gene expression changes and identify protective mechanism(s) in D. melanogaster after exposure to severe (1% O2) intermittent or constant hypoxia.
Harries et al. (2001) used the human liver HepG2 cell line to investigate gene expression changes of two hepatotoxins.
Here, we take an RNAseq approach to investigate gene expression changes associated with increased temperatures in juvenile Chinook salmon.
