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To fully evaluate the combination effects of paclitaxel and CYC3, 8 × 8 concentration combination experiments were performed in MIA PaCa-2 cells using SRB assays at 72 h; investigating concentration ranges of 0.03 30 nℳ of paclitaxel and 0.25 3 μℳ of CYC3.
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Previous studies investigating concentrations of 0.1-10 0.1-10 revealed an anti-cancer effect without any evidence for hormesis [ 27– 29].
The magnitude of quenching depended linearly upon the concentration of aniline in the investigated concentration range of 10 10 µM.
These surfaces became superhydrophobic for the highest investigated concentration of silica.
The results show that experiment and theory agree very well for the investigated concentration range of Mn (0 8%) and Ni (11 30%).
This method, together with the symmetrized structure-based (Gō) model, minimizes the need for expensive many-protein simulations, providing a convenient framework to investigate concentration effect.
Good linear relationships were provided over the investigated concentration ranges (the values of R2: 0.9997 for Baicalin, 0.9992 for Baicalein, and 0.9983 for Wogonin, respectively).
Such manipulations will allow to generate and investigate concentration gradients of biological factors or to analyse cell matrix interactions under defined conditions in a supportive in vivo environment.
The calibration curve is linear in the whole investigated concentration range from 0.02 to 0.38 μM and gave a value of 1.22 μA μM−1 for the sensitivity.
Figure 1 Extinction coefficient as a function of SWCNH concentration, for the whole investigated concentration range.
Yeasts were not susceptible to NFAP in its investigated concentration range.
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