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The investigated tools combine modelling based on first engineering principles and data based modelling into a modelling cycle that facilitates use of statistical methods with the aim of synthesizing more reliable models for prediction in a systematic way.
In clinical practice, tumour antigen-loaded DCs are intensively investigated tools to elicit antitumour immune response.
The diagnostic potential for all investigated tools was better than chance (i.e. the AUC was higher than 0.5) but none of them had an AUC above 0.75 which has been stated to be the threshold value for clinical usefulness (72).
As discussion forums were not included in our original classification scheme, findings are presented both for all included studies and for studies that investigated tools other than discussion forums.
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Primatologist Carel P. van Schaik and biological anthropologist Cheryl D. Knott further investigated tool use in different wild orangutan populations.
This experimental paradigm was similar to that developed by Savage-Rumbaugh, Rumbaugh, and Boysen [20], which investigated tool transfer mediated by symbolic communication between chimpanzees.
In this context, immunohistochemical (IHC) localization of p16INK4a (henceforth p16) seems to represent one of the most widely investigated tool.
However, despite the potential influences of self-reporting bias this is a common investigated tool used for diabetes surveillance [ 7, 8, 12].
Therefore, in this research it is considered and is focused to investigate tools in CF which is as innovation this paper.
A previous systematic review investigating tools for direct observation and assessment of clinical skills found similarly few studies describing educational outcome.
This project will investigate tools that can be used to support ingestion and translation of public health meaningful use data in the HL7 formats.
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