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The fact that the Ala/BCAA and Gly/BCAA ratios are highly correlated with the duration of hypoxia can be partially explained by the reduction of the metabolic noise by relating the measured concentrations to parameters that are not involved in the investigated pathway but that reflect variations in, e.g., analytical factors and absorption rates [33].
We further investigated pathway level impact of somatic mutations against gene networks with actionable drugs.
Interestingly, the greatest value in the comparison EAL cichlids vs. Nile tilapia is reached by ara, the key gene of the here investigated pathway.
We then investigated pathway enrichment considering the set of CNVs deemed functional through the association between the corresponding transcript levels and the copy number states and focused on those which also show differentiation across populations.
In a final thermochemical test, we investigated pathway iii, whereby the homolytic O O bond breaking is followed by an initial electron transfer from benzene to iron(IV oxo prior to the C O bond formation step.
We determined the prevalence of protein expression for each marker, investigated pathway integrity by evaluating the correlations between individual markers as well as between markers and risk factors/clinico-pathologic features, and we examined the prognostic significance of the markers on the survival of ESCC cases.
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As the measured metabolites are scattered across the investigated pathways, local network properties (e.g., connectivity) may have a negligible discriminatory power.
We investigated pathway-associated individual ESTs whose levels were greatly upregulated upon ND.
In Figure 8 is reported the representation of the investigated pathways.
We investigated pathways leading to inflammasome activation downstream of purinergic receptors.
We also investigated pathways and gene regulatory networks that might involve in the developmental control of muscle divergence.
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