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Observational studies have shown that it is not uncommon that patients with septic shock receive more than 125 ml/kg during the first hours of resuscitation [22] suggesting that the investigated doses are similar to those used in clinical practice.
It is clear to see from these tables that the values of residual turbidity of DS coagulant are higher than that of A coagulant at all the investigated doses from 10too 100 mg/L for three tested levels of low, medium and high synthetic turbid water.
Haematological toxicity of MAG-CPT at the investigated doses and schedule was mild.
At the investigated doses, the addition of TP and AVP reduced NE requirements without changing sublingual microvascular blood flow.
In conclusion, volasertib monotherapy at the investigated doses showed a clinically manageable safety profile and anti‐leukemic activity.
Apparently, the combination of both drugs at the investigated doses does not confer a higher incidence of hand foot skin reaction than either drug alone.
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A significant difference between all investigated dose metrics of responding lesions and non-responding lesions was found (Table 3).
Despite the density of the generated defects, a constant output current was observed up to the highest investigated dose of 59.9 Mrad.
Thus, the investigated dose and duration cannot be extrapolated to all patients.
The safety of rFVIIa was established in these trauma populations within the investigated dose range.
Although the investigated dose was effective, it was not sufficient to normalise fat absorption in this study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com