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All investigated agents induce decrease in protein phosphotyrosine level in leukemic cells, but differences in intensity of decrease and in pattern of proteins with decreased pTyr level were observed.
The following day investigated agents were added at indicated concentrations.
The absence of antibodies to the investigated agents in FP may be explained by several factors.
TK6 cells were exposed to the investigated agents at concentrations as shown in Figs. 1 and for 4 h.
Altogether, immunotherapeutics and kinase inhibitors are currently the most investigated agents with encouraging interim results on MEK inhibition.
In this study we investigated agents that target the dendritic cell (DC) because of the powerful role of the DC in stimulating and orchestrating anti-tumor responses.
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On the first hand, the toxicity profile of MTA must be evaluated likewise every investigated agent.
The most investigated agent to date is bevacizumab (Avastin™; Genentech).
Perfluorohexyloctane (F6H8) is the most extensively investigated agent belonging to a group of fluorinated hydrocarbons: the semifluorinated alkanes (SFA) [ 10].
Often, the task of investigating agents in such cases falls to the local police department.
Ciccolo maintained a Facebook profile page under the name Ali al-Amriki, according to investigating agents, on which he expressed an interest in dying for Islam.
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