These findings prompted us to investigate the function of LoNA in neurodegenerative diseases.
We are using xenograft and transgenic mouse models to investigate the function of EMT-related miRNAs.
To investigate the function of POFUT2 in sporozoites, parasites were propagated through mosquitoes and dissected from salivary glands.
To investigate the function of JMJ13, which removes H3K27me3, we generated JMJ13-GFP (JMJ13ox) over-expressing transgenic plants.
In the years after receiving the Nobel Prize, Dr. Perutz continued to investigate the function of hemoglobin, in both health and disease.
CNOT2 showed the strongest effects on derepression of MHC II genes thus prompting us to investigate the function of this subunit in further detail.
Here we apply the same approach to investigate the function of sieves/strainer vessels, providing direct chemical evidence for their use in milk processing.
Moreover they could be used to investigate the function of other midbrain nuclei.
To investigate the function of myosin VI in zebrafish, we cloned and examined the expression pattern of myosin VI, which is duplicated in the zebrafish genome.
Rapid, cost-effective, and quantitative approaches to simultaneously investigate the function of precise genomic alterations in vivo will help uncover novel biological and clinically actionable insights into carcinogenesis.
To investigate the function of Bmp8a, we have inactivated the gene by homologous recombination.
