In other words, application of the technique in animal models clearly creates multiple opportunities either in using animal models and pharmaceutical compounds to investigate the technique, or either in using the technique to investigate pathologies and potential treatment regimes.
Similar compartment modeling approaches have also been used to consider oxygen transport in the brain microcirculation (Sharan and Popel 2002), and to investigate pathologies such as the onset of edema, hypertension, and hydrocephalus (Linninger et al. 2009).
We only investigated pathology in our animal model at a single time point.
In summary, based on the obtained data we postulate that during inflammation related to IR the target peripheral tissues (adipose tissue, liver) secret a set of unique proteins which could serve as tissue-specific biomarkers related to the investigated pathology.
Intuitively, it seems reasonable to suggest that an efficient miRNA pair should include two plasma miRNAs, which share common properties (for example, miRNAs secreted/excreted by the same mechanism, miRNAs bound to the same protein in plasma or present in similar exosomes, etc)., but differ in their response to investigated pathology.
If defects were associated with pathology it could diminish the usefulness of automatic segmentation in clinical and diagnostic studies and particularly in those investigating pathologies where hippocampal lesions are expected (e.g. Alzheimer's disease, hippocampal sclerosis).
*vmax and vmin are axial flow velocities Quantitative mapping of pulsatile blood flow could be of particular interest for investigating pathologies in diseases such as glaucoma or diabetic retinopathy as well as vessel occlusions.
This article aims at summarizing the findings of these studies and at discussing their methodological specificities, as well as the relevance of the Rorschach test as a tool to investigate this pathology.
The present study, therefore, was designed to investigate the pathology of camel TB and identify the causative agent using molecular tools.
These animals were included for comparative analysis of post-mortem neuropathological changes at these time-points to investigate the pathology underlying MRI signal changes at 1 and 3 wks in vivo.
