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Thereafter, transcriptional study including cDNA microarray in combination with suppression subtraction hybridization (SSH) was used to investigate gene expression changes in the mutant, and a total of 267 differentially expressed genes were detected [ 12].
Therefore, a transcriptional study including a cDNA macroarray in combination with suppression subtraction hybridization (SSH) was used to investigate gene expression changes in the MT, and a total of 368 differentially expressed genes were detected [ 22- 25].
To investigate gene expression changes possibly related to the growth rate recovery, quantitative reverse transcriptase PCR and 2DE proteomic studies were performed.
These findings further underline that transcriptomics approaches described represent a useful way to investigate gene expression changes in Hbt. salinarum.
In addition, we also analyzed the testicular transcriptome of VRK1-deficient mice using DNA microarray and quantitative RT-PCR to investigate gene expression changes of specific markers during the first wave of spermatogenesis in postnatal mice.
Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium tuberculosis, a major human pathogen, and its human host cells, macrophages and dendritic cells.
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Several other studies investigated gene expression changes in postmortem tissue of patients with MD, with or without suicide (Table 1).
To address this point, we investigated gene expression changes of the 53 qPCR-validated Klf5 targets, following KD of each single Klf.
Many of these studies investigated gene expression changes in PC12 but few have evaluated the suitability of HKGs as normalizers in this model.
We have recently investigated gene expression changes at several time-points after chronic administration of heroin or methamphetamine to associate drug-induced molecular changes with long-term behavioral adaptations e [ 32].
The list of ToxArray™ genes was compiled from our own data, as well as extensive information from published studies investigating gene expression changes, assessed using microarrays or other technologies, following toxicant exposures.
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