Sentence examples for inversely regulates from inspiring English sources
Fibulin-5 inhibits cell migration and invasion and inversely regulates MMP-7 abundance in HCC cells.
Moreover, this work revealed a novel mechanism by which a ligand inversely regulates two receptors to promote angiogenesis.
Interestingly, our data indicate that Fibulin-5 inversely regulates the abundance of MMP-7 protein in HCC cells.
Having shown that CD44 palmitoylation inversely regulates cell migration, we sought to examine whether migration itself might alter CD44 palmitoylation.
TNF-α mainly inversely regulates miRNAs expression associated with myoblast differentiation while IGF1 both, promotes and antagonises myogenesis associated miRNA expression.
Moreover, it was recently demonstrated that, in adenocarcinoma of the pancreatic duct, S100P-binding protein inversely regulates Cat X expression – lower levels of S100P-binding protein increased Cat X, cell adhesion and metastatic potential of pancreatic cancer cells [ 42].
Together, these data indicate that positive regulation is more frequently performed by CepR compared to CciR, that the majority (92%) of co-regulated genes were inversely regulated by CepR and CciR and that CepR regulation can be dominant over CciR regulation.
Also, there were cases of inversely regulated genes, 14% down regulated in regions of DNA gain and 9% up regulated in regions of DNA loss.
Intriguingly, a significant number of these BACH2-regulated genes are inversely regulated by harmine, suggesting that harmine may help reverse BACH2-axis defects, for example in IBD.
Syntaxin 3A was found to be inversely regulated: It was weakly up-regulated in consequence of an increased Aβ42/Aβ40 ratio (p = 0.159, fold change 1.4), whereas it was down-regulated in consequence of a decreased one (p = 0.00268, fold change = −3.7).
Among these proteins, 43 were co-regulated in both highly pathogenic groups, while the remaining 56 were inversely regulated, i.e., up-regulated in one highly versus weakly pathogenic comparison group and down-regulated in the other comparison group.
