Sentence examples for invasive function from inspiring English sources

These unique insights into the effector molecules governing eHsp90 dependent invasive function in GBM highlight new approaches to curtail the aggressiveness associated with this malignancy.

A distinct feature of 10A-TG2 sheroids was the gain of invasive function; many cells escaped from the acini and invaded the surrounding matrix (Fig. 3C, inset).

Further investigations on whether miR-155 finally has EC protective or invasive function are needed.

In contrast, Y477F ezrin colonies showed no actin-rich protrusions, indicating a loss of invasive function; while strong actin staining in the cortical region of cells was evident.

In this capacity, TG2 can promote protein-protein interactions, resulting in constitutive activation of cellular events needed for increased cell survival and invasive function during advanced-stage cancer.

More recently, CIP2A expression has been found to be associated with synovial hyperplasia and invasive function of fibroblast-like synoviocytes in rheumatoid arthritis (Lee et al, 2011).

Our results show that TG2 expression promotes drug resistance and invasive functions by inducing epithelial-mesenchymal transition (EMT).

In contrast, these invasive functions are selected against in CF chronic infection leading to less virulent but more persistent phenotypes including alginate producing mucoid strains [7].

These data highlight the invasive functions of Runx2 in breast cancers.

More importantly, cell surface RHAMM can have invasive functions similar to CD44 and can even substitute for CD44 functions [ 143].

Our results provide evidence that TG2's aberrant expression in drug-resistant and metastatic cancer cells facilitates cell survival and invasive functions independently of its transamidation activity.