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The net result can be a degree of polypharmacy which becomes both burdensome, potentially dangerous [ 42 ], and non evidence-based – since patients with multi-morbidity are almost invariably excluded from clinical trials [ 43 ] Patients may also make an informed choice to reject medication that needs careful monitoring because of the necessity of frequent clinic visits and/or blood tests.
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Policies covering business activities almost invariably exclude liability arising out of the personal activities of the insured.
Luiz Rocha of Hope for Reefs, a campaigning initiative of the California Academy of Sciences, says large remote MPAs "invariably exclude the only areas that would benefit from spatial protection, those close to the shore.
Kenny Frederick, head of George Green's school in south-east London The biggest issue for me is that for-profit schools will inevitably and invariably exclude the hardest-to-teach pupils.
Victims of state failings are in a uniquely difficult situation: before-the-event legal insurance policies invariably exclude claims of this nature and – in contrast with this case – compensation is usually extremely modest: "just satisfaction" for a violation by the state of the most fundamental of human rights – the right to life - might be reflected in no more than £15,000 damages.
As a result, systematic reviewers tend to start the study selection diagram with the number of bibliographic citations (not studies) as the unit of analysis, usually (but not invariably) excluding duplicate citations from different bibliographic databases.
Any professional regulatory project will, for instance, invariably exclude some practitioners from entry; how to do so fairly and consistently may pose particular challenges in regulating TCAM practitioner groups.
This is consistent with the previous findings by others [ 40], suggesting that in contrast to EBV-infected B cells in which EBV infection persistently takes place in cultured B cells, an in vitro environment invariably excludes the EBV genome from epithelial cells.
Secondly, our approach represents an all-or-nothing detection, that is, methylated DNA templates (above the detection threshold) always provide strong signals/peaks so that misinterpretations (false positives) can almost invariably be excluded.
Since chimeric sequences in GSS would invariably produce lower bit scores, they were generally excluded form the contig.
Genes either lowly or invariably expressed across all patients and time points were excluded, leaving 116 out of 379 miRNA for further analysis.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com