By current practice, the Legislature sets the district boundaries, with each house drawing lines to protect its members and the final product almost invariably challenged in court.
Jesus made friends amongst the poor - sinners, prostitutes, the mentally ill, widows - and he invariably challenged the wealthy over their pride and complacency.
Facing a much larger world, microbes are invariably challenged with ever-changing environments where temperature, pH, chemicals, and nutrients are in a constant state of flux.
Because economics is a disputatious subject, and surprising empirical findings invariably get challenged by rival groups of researchers.
Even though those jobs are at one of the lowest rungs of the judiciary, these candidates must be well funded and well versed in election law, since their nominating petitions will invariably be challenged by the party regulars.
Consequently, little is known about the natural history of bulbar deterioration, and clinicians invariably find it challenging to predict the rate of speech and swallowing decline.
This means that the carrying out of research in these setting invariably presents challenges of a different order to those in higher income countries.
The expectation that men cannot (or will not) talk about depression was not borne out, challenging generalisations that men invariably demonstrate their strength through silence and stoicism (see also [ 45] for similar results).
For instance, determining the independent roles of neurotransmission and spiking on various forms of plasticity has proven challenging since manipulation of neurotransmission invariably affects spiking levels, and vice versa.
