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By current practice, the Legislature sets the district boundaries, with each house drawing lines to protect its members and the final product almost invariably challenged in court.
Jesus made friends amongst the poor - sinners, prostitutes, the mentally ill, widows - and he invariably challenged the wealthy over their pride and complacency.
Facing a much larger world, microbes are invariably challenged with ever-changing environments where temperature, pH, chemicals, and nutrients are in a constant state of flux.
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Unfailingly courteous, his contributions were nonetheless invariably challenging.
Patients with bilateral subcondylar fractures and facial-dental trauma are invariably challenging.
Because economics is a disputatious subject, and surprising empirical findings invariably get challenged by rival groups of researchers.
Even though those jobs are at one of the lowest rungs of the judiciary, these candidates must be well funded and well versed in election law, since their nominating petitions will invariably be challenged by the party regulars.
Consequently, little is known about the natural history of bulbar deterioration, and clinicians invariably find it challenging to predict the rate of speech and swallowing decline.
Doing absolutely nothing is invariably his default position when challenged over anything.
They are the chief spokespeople, and if they are challenged, it is invariably by members of the same club.
Thus, the C61-LNP treatment regimen resulted in a significant improvement of the EFS outcome in NOD/SCID mice challenged with an invariably fatal dose of patient-derived BPL xenograft cells (P-value: < 0.0001 for C61-LNP vs. control and C61-LNP vs. TBI comparisons) (Fig. 3).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com