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You cannot invalidate that.
To be sure, some (many) of them ended up losing their jobs when the bubble burst, but that doesn't invalidate the point: pushing sub-prime mortgages onto folks that couldn't afford them was a lucrative business, and the people who were involved in it it were simply reacting to the price signals that the market was providing to them.
This is a legislature-centered argument: one that points to features of *legislatures*, as grounds for courts to refrain from invalidating *statutes*.
that the cytotoxic effect was caused (only) by an inhibition of topoisomerase I but it might be an involved mechanism in cytotoxic procedures until further work corroborate or invalidate this point of view.
It would have been interesting to confirm (or invalidate) this point by including the capsid sequences of the DAV and permutotetraviruses in the analysis but, as explained above, we were not able to obtain convincing alignments for these virus proteins.
Nothing in what has happened invalidates that idea.
See how invalidating that could feel?
Specifically, my gut feel is that you allow valid clicks as long as people click fewer than ~4-6 rapid-fire clinks in a minute, and then after that point you invalidate their clicks within a very short session period, probably around an hour or two, but you do not go back and do what everyone would expect you to do and invalidate the first ~4-6 clicks.
We legitimize our identities through medical steps that invalidate whatever life we've lived up to that point.
I'm not sure if that invalidates my point or not.
At that point in my life, all I needed to be was invalidated, to hear "Yes, Hayley, it was your fault".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com