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These numbers are in stark contrast to previous estimates of the risk of dual resistance of approximately 1 in 10,000,000 cases before the introduction of therapy [7], [17], [18], [19].
In prostate cancer, if the scan taken 3 months after introduction of therapy shows worsening of disease, there is a high probability that this is real.
Two patients (0.95%) died before the introduction of therapy, but the remaining 208 were treated, 99 (47.14%) with Metronidazole + Vancomycin, 58 (27.62%) with Vancomycin and 42 (20%) with Metronidazole.
These IFNα-induced proteins were not associated with disease activity but were weakly associated with elevation of serum muscle enzyme levels (P < 0.05) prior to the introduction of therapy.
Although the potential of electrons to kill cancer cells through the loss of their kinetic energy has been made use of in radionuclide cancer treatment for more than 50 years (since the introduction of therapy of thyroid cancer with I [ 6]), the therapeutic potential of positrons has remained unexplored.
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Unfortunately, the introduction of therapies targeting Fas with agonistic antibodies has been hampered by liver toxicity (Ogasawara et al, 1993).
The successful introduction of therapies targeting tumor necrosis factor α (TNFα) has led to significant improvement in JIA outcomes.
The introduction of therapies targeting the epidermal growth factor receptor (EGFR) has recently improved prognosis in SCCHN patients.
More importantly, the introduction of therapies directed against specific molecular targets has steered the use of oral drugs into the heart of daily oncology practice.
The one common thread in all of the neonatal disasters outlined above is the uncritical introduction of therapies without adequate evaluation.
The median overall survival (OS) has increased by > 12 months since the introduction of therapies using biological compounds and doublet/triplet chemotherapy regimens [ 8].
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onset of therapy
introduction of rehabilitation
orientation of therapy
emergence of therapy
introduction of radiation
possibility of therapy
introduction of therapeutic
contents of therapy
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introduction of multiculturalism
introduction of celebrity
introduction of Coronation
introduction of perspective
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introduction of plastic
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