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An important factor in revolutionizing treatment for acute coronary syndromes in recent years has been the introduction of potent new antithrombotic and antiplatelet pharmacologic therapies such as low-molecular-weight heparins and glycoprotein IIb/IIIa inhibitors.
Introduction of egg and fish into the diet can be made after 6 months but the introduction of potent food allergens (kiwi, celery, crustaceans, seafood, nuts, especially tree nuts and peanuts) should be delayed after 1 year.
Since the introduction of potent combination anti-retroviral therapy (ART), a reduction in AIDS deaths nationally, including inmates in correctional settings, has been reported [4].
Despite the successful introduction of potent anti-cancer therapeutics, most of these drugs lead to only modest tumor-shrinkage or transient responses, followed by re-growth of tumors.
While much has been achieved with the adoption of existing preventive measures and the introduction of potent drugs that severely reduce viral load, there is still a pressing need to develop additional prevention options, such as HIV vaccines, to drastically reduce the number of new infections.
Despite the introduction of potent NAs, HBV still cannot be cured by NAs alone.
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Oral formulations and the introduction of highly potent bisphosphonates may offer advantages, and require clinical assessment.
It took 15 years from the first recognition of AIDS for the introduction of the potent combinations of antiretroviral drugs that now extend the lives of many people with AIDS.
Brain cancer is rare: only about 7 cases are diagnosed per 100,000 men and women in America per year, and a striking increase, following the introduction of a potent carcinogen, should be evident.
The incidence of lymphomas has declined since the introduction of more potent anti-H.I.V. drugs in 1996, but, for unknown reasons, it has declined less than Kaposi's sarcoma and many other serious complications of AIDS, said Dr. Harold W. Jaffe, an AIDS expert at the Centers for Disease and Prevention in Atlanta.
The recent introduction of the potent immunosuppressive agent sirolimus has afforded an opportunity to develop a regimen designed to maximize prophylaxis of early acute rejection, absent drug-induced nephrotoxicity.
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