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Intentional modifications of LIB electrodes may also lead to the introduction of point defects.
Deletion or introduction of point mutations that disrupt the miR-466g target site attenuated miR-466g-directed suppression of luciferase activity.
As a second alternative, the stability of a suboptimal framework can be improved by the introduction of point mutations designed to optimize key residue interactions.
In addition, the pH sensitivity of GFP could be modified by introduction of point mutations [30].
Although the introduction of point sprites ensure that all points contributing to the screen pixels are rendered, discrete points cannot create a smooth fluid surface.
From a cellular perspective, risking the introduction of point mutations during translesion synthesis may be preferable to resorting to more drastic mechanisms of DNA repair, which may cause gross chromosomal aberrations or cell death.
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The introduction of point-of-care testing for cardiac troponin has the potential to reduce turnaround time for assay results, compared with central laboratory testing, optimizing resource use.
In Mozambique, the introduction of point-of-care CD4 counts in primary healthcare clinics doubled the number of patients on ART and halved the time it took for patients to start treatment.
In recent years, the introduction of point-of-care US performed by clinicians has been successfully implemented in a variety of settings.
The introduction of point-of-care HIV rapid tests has transformed the epidemic, particularly in low- and middle-income countries.
The introduction of point-of-care (POC) D-dimer tests facilitates a similar diagnostic strategy in primary care.
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