Research activities may also lead to the introduction of new practices, protocols and the identification or awareness of problems at the research site.
Efforts to increase CC screening coverage were initiated in 2006 within the public sector with the introduction of new screening protocol [ 5].
The introduction of a new protocol (ALL-10) at the start of this study limited the number of possible participants.
With the introduction of the new protocol more attention is paid to secondary prevention and the prescription of medication, e.g. aspirin and statins.
Twenty patients underwent RCA-CVVH with protocol A while, after introduction of the new protocol, 20 patients were treated with RCA-CVVHDF according to protocol B. Clinical characteristics of the patients at the time of starting CRRT have been compared and reported for both groups in Table 1.
In contrast to the marked improvement in early results, the rate of long-term survival of solid-organ allografts has improved only slowly over the last few years despite the introduction of new and potent immunosuppressive protocols, better organ-preservation techniques, and advances in perioperative management.
Immunological discoveries, the introduction of new medications, and the improvement of the immunosuppressive protocols have led to a further development of transplantology.
In fact, considering the 'hot drugs' waste, the application of our protocol produced a saving of €24,3477 in 2007, €22,4033 in 2008 and €21,0677 in 2009 (that is 32%, 29 % and 27 of the iv drugs waste costs) in addiction to over € 90,000 per annum saved since 2006 (when comparing to the pre-protocol era) even after the introduction of new high cost drugs.
As new evidence-based medicine continues to evolve and guidelines and protocols continue to be periodically updated, along with the introduction of new technologies such as electronic prescribing, clinical decision support or bar-coding, a given set of FMEA results will only be valid for a limited time period and should therefore be updated regularly.
Introduction of new standards of economic measurement.
