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This isn't to argue against the introduction of labelling.
The introduction of labelling techniques using stable isotopes (e.g. isotope coded affinity tag – ICAT [25]) was a key to the success of quantitative proteomics.
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They included the new marketing restrictions, a ban on new bars opening near mosques, and the introduction of labels warning consumers that "alcohol is not your friend".
Immunoassays involving sample incubation followed by a wash step prior to introduction of labeled analyte are potentially subject to both positive and negative interference (bidirectional interference) by a competing ligand.
Complete introduction of label into culm was achieved for every plant.
We randomized the labeling of the reference sample in each set to prevent any inadvertent introduction of labeling bias.
The introduction of labels providing an additional negative charge leads to an increase in retention times, but a change or enhancement in selectivity is not to be expected.
This binding is usually followed by introduction of labeled secondary antibody and by monitoring the resulting signal, which is greatly amplified through action of enzymes or nanoparticles (section 9.2).
Protein separation and identification technology has evolved rapidly in the past 5 years with the introduction of label-free liquid chromatography/mass spectrometry methods that can more accurately identify and quantify peptide species.
Introduction of labels : Glycan labeling mainly has two functions in electrophoretic separation techniques: On the one hand, labels enable or facilitate fluorescence or MS detection; on the other hand, they enhance or in the case of neutral glycans allow the separation by introducing a charge on the glycans, thus allowing electrophoretic mobility.
The advent of mass spectrometry enabled the introduction of sophisticated labelling techniques, e.g. stable isotope labelling with amino acids in cell culture (SILAC [46]), ICAT [25] or isotope tags (iTRAQ [47,48]).
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