Sentence examples for introduction of gene expression from inspiring English sources

Since the introduction of gene expression microarrays in the mid-1990s, genome-wide exprofilingprofiling has been widely utilized in cancer research [63], [64].

Many gene expression signatures were developed since the introduction of gene expression microarray technology, however, so far only in breast cancer two prognostic gene profiles are tested in large prospective trials (Bogaerts et al, 2006; Sparano, 2006; Wirapati et al, 2008; Weigelt et al, 2010).

Meanwhile, large multi-centre studies — e.g. the Microarray Innovations in LEukaemia (MILE) study 10 — prepare for a standardised introduction of gene expression profiling in diagnostic algorithms, aiming to translate this novel methodology into clinical routine for the benefit of patients with the complex disorders.

However, the introduction of gene expression microarrays more than a decade ago promised that the use of quantitative assessment of all genes, rather than hisopathological subjective assessments or measurements of the expression level of single genes or proteins, would offer a more precise determination of the continuous tumor biology and outcome in breast cancer.

This supports Assumption 12 (see Introduction) that rates of gene expression are influenced by temperature.

We use the evidence presented in the Introduction to assume patterns of gene expression and that the amounts of expression adhere to phenotypic observations to infer apparent expression levels.

Gene function may be monitored by examining the perturbations of gene expression after introduction of either normal or mutated genes.

The introduction of techniques for simultaneous measurements of gene expression for thousands of genes in a single analysis using microarrays allows a more comprehensive picture of the host response during infection with A. pleuropneumoniae.

RNAi denotes the highly specific posttranslational silencing of gene expression that occurs in response to the introduction of double-stranded RNA into a cell.

A limiting factor in the study of gene expression of wild-caught animals is the introduction of stress which can lead to behavioral alterations.

The objective of our study was to characterize alterations in patterns of gene expression in the equine endometrium in response to the introduction of bacterial pathogens.