Sentence examples for introduction of a point from inspiring English sources

After introduction of a point mutation into this seed sequence the construct is no longer repressed by injection of miR-10 (figure 2C).

We found that introduction of a point mutation (N178Q) into the HD DNA binding domain, deletion of the transcriptional repression domain (ΔTN), or deletion of the specific domain (ΔSD), each resulted in a loss of oncogenic rescue activity following knockdown of endogenous NKX2.2.

We report that optimal in planta cleavage requires the addition of an N-terminal nuclear localization signal and introduction of a point mutation to increase DNA cleavage activity.

This method is most useful for large-scale genomic changes, rather than smaller-scale changes, such as introduction of a point mutation or a sequence encoding a tag.

The introduction of a point mutation into the LRR abolished this dominant negative effect, indicating that a functional leucine zipper motif is essential for the antimorphic activity of truncated ERECTA proteins.

Introduction of a point mutation, R122I, that abolishes F2 DNA binding without affecting the structural integrity of the domain [18] rendered the sumoylation reaction insensitive to DNA (Fig. 2D).

We empirically investigate the deterrent and offsetting effects of the introduction of a point-record driving license (PDRL) in Italy.

One change could be the introduction of a points system similar to that operated by Australia and Canada.

In those early days there was no points system, it was only after 1890 that a format allowing the introduction of a points system was provided.

We also aimed to report changes that occurred in relation to the introduction of a point-of-care AChE device [ 7].

Hence, introduction of a point-of-care test for anti-HBs in a pre-vaccination screening phase for HCWs could be cost-effective.