At the first cardiac evaluation, 20±16 months after pegvisomant introduction, IGF1 levels normalized in 29 (69%) of the 42 patients.
The introduction of AZA (2 mg/kg/day) normalized IgG4 levels, eliciting the total withdrawal after 17 months.
Of note, if Gapdh were chosen as reference for highly/lowly glucose sensitive beta cells, much of their observed differences would remain unnoticed, illustrating the inevitable introduction of interpretative bias by normalizing.
Moreover, the introduction of an automated procedure to normalize the readout from the analytes allowed us to obtain semi-quantitative results.
Similarly, introduction of the 35S::EXOga construct did not normalize the phenotype of the BR-deficient det2 mutant ([ 25], data not shown).
Fig. 9 Normalized TEER values of BBB model recorded after the introduction of nanoparticles with magnetic explosion periods.
Indeed, introduction of a constitutively active GLI3 repressor in a Ptc1-deficienct background normalized the renal phenotype, restored the normal domain of HH signaling activity and rescued expression of genes specific to ureteric tip cells and required for their functions.
In general, such fundamental assumptions are preferable to the introduction of extra parameters, e.g. to using the Box-Cox transformation to normalize the data.
As explained in the introduction, manipulability is a variable that influence behavioral performance on cognitive tasks [50] and thus deserves to be normalized.
"In a sense," he says in an introduction, "Hitler will be 'normalized' — although this will not make him seem more 'normal.' If anything, he will emerge as even more horrific".
