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An important limitation is our lack of information about the tamoxifen treatment in the individual patients, which introduces exposure misclassification.
This introduces exposure error and likely biases the effect estimates downward (Armstrong 1998; Zeger et al. 2000).
PM2.5 concentrations vary spatially within the study domain and thus using only available monitors introduces exposure error and likely biases the effect estimates downward [ 17].
Conversely, the ITT last observation carried forward approach introduces exposure as a variable which becomes an increasingly significant issue as trial duration increases (eg, the relevance of summarizing efficacy at extremes of the exposure range is questionable).
One of the rationales for conducting biomonitoring using a local HANES was the premise that the urban environment introduces exposure opportunities that differ from the nation as a whole.
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Advanced fitness functions are presented, accounting for the total installation cost in a realistic way, and introducing exposure sensitivity levels per room.
As a measure of lack of sleep, this question may introduce exposure misclassification and bias our results.
Furthermore, population migration could introduce exposure misclassification [ 30].
Incomplete information on residential mobility may introduce exposure misclassification.
This might introduce exposure misclassification bias (Berkson error).
While this likely introduced exposure misclassification, the impact of this bias may mitigated for several reasons.
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