Sentence examples for introduces conformational changes and from inspiring English sources
Phosphorylation often introduces conformational changes and makes proteins more hydrophilic.
We speculate that CC2D1A binding to phospholipids [ 17] at the membrane introduces conformational changes exposing the PDE4D5 (S126) allowing its phosphorylation and activation.
The binding of Zn II) to ZntR converts it into a transcriptional activator protein that introduces conformational changes in the DNA which apparently make the promoter a better substrate for RNA polymerase [ 29].
For yeast it was shown that the accurate removal of spacer sequences introduces conformational changes that allow the pathway to proceed to the next step (Cote et al, 2002).
The binding of zinc-bound ZntR to the promoter introduces conformational changes in the DNA, which apparently make the promoter a better substrate for RNA polymerase, thus strongly activating the transcription of the zntA gene and increasing the efflux of zinc from the cell [ 29].
Although binding of proteins to the JMD of P-cadherin has been documented only for p120-catenin [ 99], we cannot exclude the possibility that its disruption introduces conformational changes or uncouples the interaction of other proteins that could be responsible for the observed effects.
S620T is a mutation that removes inactivation, and that is suspected to introduce conformational changes in the outer pore region in hERG.
The cDNA in this study, PM/Scl-75c-β, has a 17 amino acid insertion at the C-terminus which could introduce conformational changes in epitope [ 47].
Formalin fixation also introduces conformational and chemical changes in DNA that lead to infidelity of DNA replication by polymerases.
So these groups restricted the conformational changes and also molecular mobility.
