Sentence examples for introduces conformational changes from inspiring English sources

Phosphorylation often introduces conformational changes and makes proteins more hydrophilic.

We speculate that CC2D1A binding to phospholipids [ 17] at the membrane introduces conformational changes exposing the PDE4D5 (S126) allowing its phosphorylation and activation.

Constitutive or ligand-dependent activation of AT1R and MAS likely introduces conformational changes in the FBM that is suitable for FLNa engagement.

The binding of Zn II) to ZntR converts it into a transcriptional activator protein that introduces conformational changes in the DNA which apparently make the promoter a better substrate for RNA polymerase [ 29].

For yeast it was shown that the accurate removal of spacer sequences introduces conformational changes that allow the pathway to proceed to the next step (Cote et al, 2002).

The binding of zinc-bound ZntR to the promoter introduces conformational changes in the DNA, which apparently make the promoter a better substrate for RNA polymerase, thus strongly activating the transcription of the zntA gene and increasing the efflux of zinc from the cell [ 29].

S620T is a mutation that removes inactivation, and that is suspected to introduce conformational changes in the outer pore region in hERG.

The cDNA in this study, PM/Scl-75c-β, has a 17 amino acid insertion at the C-terminus which could introduce conformational changes in epitope [ 47].

Formalin fixation also introduces conformational and chemical changes in DNA that lead to infidelity of DNA replication by polymerases.

It has been shown that the binding of SRP19 to 7S RNA introduces some conformational changes in the RNA molecule, which enables SRP54 to bind it.

A major constraint that guided us to introduce the conformational changes in order to obtain the intermediate state relates to the open-state stabilizing interactions between two neighboring VSDs.