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For the simulations we have used parameter values and initial conditions introduced therein and reproduced in the Table 1 of the Additional file 1.
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We introduce therein the discrete notation employed in this manuscript and provide a useful vector representation of our method.
Both the CSNB2-associated point mutation Cav1.4 L860P [14,15] referred to as p.L849P in these publications and the truncation mutation Cav1.4 R1827X ([ 15]; referred to as p.R1816X therein) were introduced into the Cav1.4 α1 cDNA previously cloned from human retina (Genbank accession number, JF701915, length of open reading frame 5898 base pairs).
We simply calculate the wave propagation using a finite difference method (FDM) (e.g. Aochi and Douglas, 2006, references therein), introducing a 3D deep structure model provided by NIED (Fujiwara et al., 2009).
The following concept was introduced in [4] (Definition 3.1 therein).
A variety of location-awareness techniques are introduced in [15] and the references therein.
Algorithm (1.1) was initially introduced in [26]; for more details see the references therein.
Since then, various types of vector variational inequalities were introduced and studied (see, e.g., [8, 9] and the references therein).
The Halpern iterative process was initially introduced in [23]; see [23] for more details and the references therein.
As a result, several bacterial species have been isolated and commercially introduced for biocontrol purposes (Steinberg et al. 2007 and references therein).
Most of the results follow the concept of two-level error estimation introduced in [42], see also the recent work [39] and the references therein.
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