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In this configuration, the system has a marked tendency to explode driven by van der Waals repulsions among the newly introduced side chain atoms.
However, also molecular interactions due to the introduced side chains may contribute.
A critical question was how the introduced side chain modifications of the pePNA components affected the in vivo knock down efficiency compared to unmodified aegPNAs.
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The Rodnina-Zaytsev team introduced side-by-side jumps consisting of double axels.
He also introduced side-by-side restarts after safety car periods so that the cars would be wheel-to-wheel from the off, saying at the time: "Danger will be an important element of the sport".
Jim Vondale, who until recently was the director for automotive safety for Ford Motor — the company that introduced side-curtain air bags in 2002 — said in a telephone interview that to meet the ejection test requirements, the curtain air bags would have to be considerably larger than those in today's vehicles.
In 2002, the company had introduced siding with a finish called ColorPlus, in a range of shades chosen without much thought by some people in the manufacturing department.
In this paper, the above singularity problem has been solved by introducing side conditions without sacrifice of convergence.
Semiflexible residues are allowed to introduce side chain flexibility during the third stage of simulated annealing and backbone flexibility during the fourth stage.
In eukaryotes, glycogenin (EC 2.4.1.186) initiates the synthesis of the linear glucan chain (2), which is elongated by glycogen synthase (GYS, EC 2.4.1.11) (3), functioning in concert with glycogen branching enzyme (GBE, EC 2.4.1.18) to introduce side chains (4).
In this structure, several amino acid substitutions in the putrescine binding pocket (Asp174 to valine, Phe111 to arginine, Leu13 to arginine, and Phe285 to histidine) introduce side chains that mimic the role of putrescine in the human enzyme.
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CEO of Professional Science Editing for Scientists @ prosciediting.com