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Consider these items, among many others: The announcement of the feature-rich next Xbox entertainment console should have been a triumph, but Microsoft set off a furor when it introduced huge changes in the way software (games) would be sold and used, including a requirement to be online.
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The curriculum is introducing huge changes, but it's only two sides of A4 in length".
Yet the fact that the change is man-made is unprecedented, which introduces huge uncertainty about how far and fast it will proceed.
The internet introduces huge social inequalities due to its functionalist downside.
After Franco's death in 1975 and Spain's return to democracy, huge changes were introduced.
"It is a bit reckless for the government to introduce such a huge change when demographics are coming up and we are coming out of recession," he says.
This might introduce a bias even for very good superposition of proteins since slight changes of the distance between protein and ligand atoms may result in huge changes in the ChemPLP scores.
"I have seen huge changes.
There really have been huge changes".
These huge changes triggered geological mayhem.
These are huge changes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com