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It is worth noting that while the same mRNA sample was used for both SAGE and 454 EST analyses, the inherent differences in the technologies used may have introduced discrepancies in gene identification.
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Consequently, in these cases, the method will introduce discrepancies, that will need further attention.
Moreover, the selection of a single centre allows eliminating the bias due to the presence of different CT systems in different departments, which might introduce discrepancies in the radiation dose burden of equivalent diagnostic protocols.
The moving nature of the heart, coupled with the possibly non-simultaneous acquisition of the anatomical and the activity datasets, is likely to introduce discrepancies between the PET and the anatomical image, that in turn might mislead lesion quantification and detection.
Local practice variations also have potential to introduce discrepancies.
45 Only 10% of these trials were reported without introducing discrepancies.
One process that can introduce discrepancies between the results produced by different platforms is the selection of the appropriate normalization algorithm.
Therefore, this is a point likely to introduce discrepancies in studies focusing on this topic, and which volume and number of times the injection should be performed needs to be standardized in future studies.
The uncertainties in measured σa, as well as inaccuracies in the inverted data, introduced some discrepancies between estimated σ and reference values in time and space.
Forward and backward translations are necessary (preferably reviewed by the questionnaire author) to ensure that the translations have not introduced semantic discrepancies.
As a result, our findings likely underestimate the risk associated with this particular issue, as we were unable to assess potential biases introduced through discrepancies between the original trial design and actual conduct.
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CEO of Professional Science Editing for Scientists @ prosciediting.com