Your English writing platform
Discover LudwigSuggestions(1)
Exact(9)
With random mutagenesis, point mutations are introduced at random positions in a gene of interest, typically through error-prone PCR mutagenesis, in which MnCl2 is added to the reaction mixture to cause a reduction in the fidelity of the DNA amplification [149].
New particles are then introduced at random
Mutations are introduced at random sites in random individuals with rate μ.
In the second method, random domain-localized (RDL) mutagenesis, a mutation is introduced at random within a specific domain of a gene.
New drift variants are introduced at random time points, leading to a sudden loss of protective immunity for part of the population and occasionally to reduced vaccine efficacy.
In the second method, termed random domain-localized (RDL, pronounced "riddle") mutagenesis, mutations are introduced at random within a single domain of a gene.
Similar(51)
For targeting with the crossing scheme, the targeting vector, which was modified to contain the appropriate homology arms (here 3-5 kb arms were used but smaller arms are likely to suffice), was introduced at a random genomic locations by P-element-mediated transformation (Rainbow Transgenics, Bestgene or in house).
Over the subsequent years a wide range of other therapies has been introduced seemingly at random: these include tumour necrosis factor alpha (TNFα) inhibitors, intravenous immunoglobulins (IVIg), Intralipid, prednisolone or dexamethasone and granulocyte-colony stimulating factor.
MICE is one of the recommended methods for multiple imputation in electronic health-record data, and we have shown that standard parametric MICE and our new random forest MICE method work reasonably well under artificially introduced missingness at random in a realistically complex data set.
A random X7 AAV display peptide library (random insert introduced at position R588 VP1 capsid protein numbering) with a diversity of 2×108 random clones (determined at the cloned plasmid level) was produced using a three-step protocol as described previously [14], [35].
As before, one user is delayed by a half-symbol interval, and in addition, a random delay is added to both users to model random delays introduced at the transmitter.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com