Sentence examples for introduce mutation from inspiring English sources

Furthermore we introduce mutation into Wright's equation and UMDA.

The engineered gRNAs were shown to direct the Cas9 nuclease for precise cleavage at the desired sites and introduce mutation (insertion or deletion) by error-prone non-homologous end joining DNA repairing.

To consider potential bias caused by copy number abnormalities, we introduce mutation cell frequency (MCF) instead of Mutation Allele Frequency (MAF).

Thus, one experimental approach we used was to introduce mutation αT349R into the wild-type background (with βArg-182) in the presence of the βR182A mutation.

The method is based on a homologous recombination in E. coli JC8679 and thus is very unlikely to introduce mutation(s) into ORFs during cloning.

Indeed, DNA fragmentation induced by formalin fixation and/or degradation due to necrosis will reduce the success rate of PCR amplification, and might potentially introduce mutation artefacts [ 39, 40].

In much C. elegans work, researchers introduce mutations or otherwise manipulate the genome to see the impact on the developing organism.

To generate the TNC-mutation promoter, multiple site-directed mutagenesis was used to introduce mutations into wild-type TNC promoter.

NHEJ can also introduce mutations during repair.

To introduce mutations to the promoter of Sprouty4, site-directed and semi-random mutagenesis was performed as previously described[44].

For Hox3, we tested two pairs of TALENs but they failed to introduce mutations.