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Furthermore, we showed that these intermolecular spaces are intrinsically occupied by tightly bound water molecules.
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Despite DNA sequences encoding nucleosome occupancy at certain regions, TF binding can drive nucleosomes to occupy intrinsically unfavorable DNA sequences or evict nucleosomes from intrinsically favorable sites.
These studies have shown that although bulk nucleosomes are not strongly sequence-specific, models trained on in vitro data can predict a subset of in vivo nucleosomes occupying intrinsically favorable sites.
2) The authors state (in the subsection "The binding pocket of Dvl PDZ is occupied by its intrinsic ligand"): "... suggesting not only that the Dvl PDZ domain binds intrinsically to the Dvl C-terminus but also that this binding interferes with interactions between the Dvl PDZ domain and its other binding partners in the Wnt signaling pathways".
Two of the statistically significant factors, the presence of transmembrane regions and the proportion of protein length occupied by sequences predicted to be loosely shaped (intrinsically disordered), refer to properties that become meaningful only after a protein chain is synthesized and folded.
Wild type mouse amelogenin and mouse-lemur chimera also occupy the intrinsically disordered region indicating that the properties of the two amelogenins are similar to those of intrinsically disordered proteins.
All occupied.
They occupied adjoining seats.
Only two were occupied.
It is 80 percent occupied.
The rooms were occupied.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com