Although the fluorescence-based bioassay was more sensitive, the technique was intrinsically compromised by the need for unknown ligands to cause fluorescence enhancement upon binding.
The reproducibility of dried droplet laser ablation is intrinsically compromised, compared to pneumatic nebulization, as a result of the additional error introduced by repeated droplet deposition and by the transient signal mode.
Siliceous grain boundary films readily corrode and compromise the intrinsically good corrosion resistance of bulk alumina.
A few survive the ordeal; most seem almost sadly compromised; others are intrinsically weak.
The sense of devotion that Lorraine displays, the idea that whatever compromise she is making is intrinsically worth it, permeates the film and hampers it, creating a world in which all men and women behave honorably and admirably.
The insularity, the familial competition, the theatrical personalities around the house, the atmosphere of commercial success and popular fame with its taint of artistic compromise, the presumption that realistic representation was intrinsically a virtue: all these factors shaped Andrew Wyeth's life and evolution.
For intrinsically high-dimensional data, the only possible solution is to compromise and use approximate or probabilistic approaches.
With the selection based only on the morphological characteristics after fertilization, seemingly appropriate but intrinsically handicapped embryos may be cultured and transferred resulting in compromised in vitro development, or low pregnancy rates, abortions and further negative consequences.
However, these systems have also the potential to compromise the quality of health care if they are misused, intrinsically faulty or entail unexpected side effects.
Since the starting material is very limited and the reaction yield is intrinsically low, even losing a small fraction of the target DNA would potentially compromise sequencing efforts.
