Sentence examples for intrinsic specificity from inspiring English sources

One approach is to modify the intrinsic specificity of TRAIL for its target Death-receptor 5 specific by substituting amino-acids located in the receptor binding interface of TRAIL [ 8].

The results of the association/dissociation and affinity kinetics of the interaction between H-ferritin and native AMB8LK or AMB8LK immunoNPs revealed similar constant values, showing that the conjugation process of the MAb to the NPs did not alter the intrinsic specificity and affinity of the MAb to the antigen.

It seems likely that local DNA methylation patterns arise not from an intrinsic specificity of Dnmts themselves, but via interactions with other DNA binding proteins.

Furthermore, the approach is limited by the intrinsic specificity of the CEL1 endonuclease and is influenced by the level of pre-existing polymorphism in target genes.

Although we did not include such studies here, the intrinsic specificity of SRM provides the merit to do so if necessary in the future.

First, some sequence motifs may be poorly characterized or may lack sufficient intrinsic specificity to allow them to be identified with confidence.

To overcome limitations set by their intrinsic specificities, we have genetically engineered the protein regions governing nucleotide sugar and acceptor substrate specificities of two urdamycin deoxysugar glycosyltransferases, UrdGT1b and UrdGT1c.

In addition, some E3s possess intrinsic linkage specificity that is independent of the respective E2 8. Substrate specificity is ensured by the diverse E3s 9. E3 ligases are divided into subfamilies according to their domain structure: HECT, RING or RBR ligases.

A novel variant of 6-deoxyerythronolide B synthase (DEBS) module 2 was constructed to explore the balance between protein protein-mediated intermodular channeling and intrinsic substrate sprotein protein-mediated

The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC).

Phosphatases have been considered promiscuous enzymes, displaying little intrinsic substrate specificity when assayed in vitro.