Sentence examples for intrinsic sequence from inspiring English sources

PWMs represent the intrinsic sequence variability of TFBS in the form of a matrix.

In vitro experiments have not revealed intrinsic sequence specificities of the Dnmt3 enzymes and more in vivo studies are needed to dissect the roles of the two proteins in de novo methylation of individual genes.

DNA, however, is a dynamic entity and the forces do get disrupted and the coding bases exposed to enzymes [5] as in replication of DNA, transcription into m-RNA etc.How DNA opens up in response to intrinsic sequence effects and extrinsic local environment is thus a matter of considerable interest in deciphering molecular details of gene expression in particular and genome organization in general.

Importantly, the two classes have low or high intrinsic sequence preferences for nucleosomes, respectively.

Similarly, is disorder an intrinsic sequence feature or is it difficult to maintain?

Given their intrinsic sequence redundancy, transcriptome-level analyses of transposable elements are scarce.

Under the protein influence, such distortions can be enhanced beyond what is observed in free DNA, but these enhanced deformations still reflect the intrinsic sequence-dependence DNA flexibility.

Then, exploiting a very large dataset of DNA/protein complexes recently presented [6], we show that proteins recognize the intrinsic sequence-specific malleability of DNA grooves.

Quantifying the overall flexibility of each of the ten complementary dinucleotide steps, the TRX scale provides fresh insights to understand how the DNA/protein interactions depend on DNA's intrinsic, sequence-dependent, malleability.

To investigate if proteins exploit the intrinsic sequence-dependent malleability of the DNA, we compared the TRX scores of free tetrameric sequences to the minor groove width values recently compiled [6] on 4426 tetramers in crystallographic DNA-protein complexes, and averaged according to the 136 possible tetrameric sequences.

Why should this be the case, given that our UDS of cloned mtDNA showed no intrinsic sequence-specific difference between the two templates?