Sentence examples for intrinsic fate from inspiring English sources
The phenotypic changes therefore may occur even in an homogenous environment and may result from asymmetric segregation of intrinsic fate determinants during cell division that lead to the change in gene expression patterns.
Results from this study imply that the two cephalic gap genes otd and ems are included among the set of intrinsic cell fate determinants for the ALl1 lineage.
As an intrinsic neural fate promoting factor, Pou3f1 is expressed earlier than the neural lineage related genes Zfp521, Pax6, and Zic1, and Pou3f1 directly binds and upregulates these genes expression.
This stereotypy has been attributed, in part, to the expression and function of transcription factors that act as intrinsic cell fate determinants in the neuroblasts and their progeny during embryogenesis.
This detailed ultrastructural description provides the foundation for further exploration of the interplay between intrinsic cell fate specification mechanisms and extrinsic signals that give rise to these complex structures.
In addition to extrinsic signaling pathways, neuroectoderm specification is also controlled by the sequential activation of intrinsic neural fate-promoting factors.
Specialized neurons are derived at exact times during development, suggesting a partnership between temporal codes and neuron-intrinsic cell fate determinants (Hirono et al, 2012; Kao et al, 2012; Ulvklo et al, 2012).
The competence model must therefore rely on an intrinsic progression in fate potential.
It will be exciting to determine whether intrinsic asymmetry contributes to fate specification in adult mammalian stem cell lineages as well.
Several recent studies in the hematopoietic stem cell system have shown the utility of single-cell time-lapse imaging to delineate symmetric and asymmetric divisions in response to extrinsic and intrinsic stimuli and cell fate choice instructed by cytokines.
Death receptors have a key role in mediating external signals to caspase8 in extrinsic pathway, and the mitochondria has a main role in deciding a cell fate in intrinsic pathway.
